General knowledge of henoch-schonlein purpura with renal2018-02-13 18:02
First, definition of purpura kidney disease
Henoch-Schonlein purpura nephritis is renal damage caused by allergic purpura.
Purpura is a vasculitis that can damage blood vessels of whole body. Damage to small blood vessels of skin, the skin will appear red dot; and the kidneys are two capillary groups, damage of kidney blood vessels, it will cause urine protein, occult blood, which is the origin of purpura nephritis.
Purpura nephritis diagnosis must meet the following three conditions:
1. Extra renal manifestations of cutaneous purpura of Henoch Schonlein purpura;
2. The clinical manifestations of kidney damage, such as hematuria, proteinuria, hypertension, renal insufficiency;
3. Renal biopsy pathological changes showed mesangial IgA deposition and mesangial proliferation.
Allergic purpura in addition to subcutaneous blood spot, but also with abdominal pain, joint pain and other symptoms. If renal damage is caused, proteinuria, hematuria, and renal failure may occur.
Second, the treatment program
A small part of purpura kidney children are transient, that is to say the symptoms will be naturally relieved over time, without treatment.
Western medicine, if the 24-hour urine protein is less than 1g, to take general treatment: to avoid contact with allergens, abdominal pain and blood in patients with obvious blood stasis can be used H2 receptor blockers, vitamin K1, atropine, etc, can also take antihypertensive, diuretic treatment according to the condition.
If the 24-hour urinary protein is more than 1 g, hormone therapy can be considered to relieve gastrointestinal symptoms, joint pain and skin purpura. The initial full amount of hormone, reduced by 10% every 0.5-1 months.
First choice of urpura nephritis patients with crescent is methylprednisolone, change to metacortandracin after the course of treatment, in addition, need to use immunosuppressive agents, such as cyclophosphamide, cyclosporine, leflunomide and so on.
Purpura kidney patients can use drugs with name of "Pulley" "Sartan" for anti-hypertension, these drugs can also reduce proteinuria, relieve renal inflammation and fibrosis.
Third, to prevent recurrence
Elimination of purpura skin doesn’t mean the disease is cured, because the lesions are still there, there is the risk of recurrence.
The key to purpura kidney relapse is the vascular inflammation caused by toxins in the body. Through the use of traditional Chinese medicine, the body will accumulate large amounts of toxins through defecation and sweat glands effectively cleared out of body, for patients with kidney disease self-healing and other drugs, to create a good environment and conditions to reduce the risk of recurrence.
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