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Is purpura nephritis serious in kidney disease?

2017-10-26 17:32

Purpura nephritis refers to kidney damage caused by allergic purpura, the causes for the allergic reaction caused by bacteria, viruses and parasites infection, or for certain drugs, food allergies, or pollen, insect bites, etc. caused by cold stimulation. Clinical manifestations in addition to skin purpura, joint swelling and pain, abdominal pain, blood in the stool, the main hematuria and proteinuria, occurred in the skin after a month of purpura, some or can also see skin purpura, abdominal pain, Symptomatic urinary abnormalities.

Clinical classification of purpura nephritis can be pided into five kinds: asymptomatic urine abnormalities, persistent hematuria or proteinuria, hypertension and renal dysfunction. Chronic purpura nephritis syndrome nephritis onset is slow, should be reported after the disappearance of nephritis persists, often accompanied by renal dysfunction, this type of adult as much. The clinical features of acute glomerulonephritis nephritis are hematuria, proteinuria, edema and hypertension. Acute onset, like acute nephritis, most belong to this type. Acute nephritis syndrome occurred in oliguria and renal damage in the prognosis of severe acute nephritis. Nephrotic syndrome, allergic purple disease, nephrotic syndrome, this is a serious glomerular disease, accompanied by renal dysfunction.

Kidney symptoms can be pided into four cases: rash hemorrhagic and symmetrical distribution of the characteristics of the disease rash. When the rash from the beginning of the red spot-like, the pressure can disappear, then gradually become purple hemorrhagic rash, touch slightly uplift epidermis, rash often symmetrical distribution in the lower limbs, ankle knee circumference is more common. Can also be seen in the buttocks and L squeak, torso rare, rash can be turned into yellow brown when the fade. Most cases of rash can have 1 to 2 times, up to 3 times repeated, inpidual patients can be continuous for several months or even years, the latter often complicated by P heavy nephritis, poor prognosis. Gastrointestinal symptoms are the most common abdominal pain, mainly to the umbilical and lower abdomen, paroxysmal colic, abdominal pain can be disgusting vomiting and hematuria, occasionally hematemesis, blood in the stool. Symptoms of about half of the joint cases of sub-permissible multiple joint disease, mostly mild pain, some cases may have joint swelling and limited mobility. The most commonly involved joints are the knee, ankle, and finger. Symptoms subside more than a few days without any deformity of the joint, but may recur during the active period. Other symptoms of lymphadenopathy, hepatosplenomegaly. The less common clinical manifestations were pulmonary hemorrhage, slight hypertension, nephritis induced hypertension, and seizures, paralysis and coma due to brain purple lesions.

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