Symptoms and causes of uremia in children

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Symptoms and causes of uremia in children

2017-04-27 14:37

Under normal circumstances, the children in the collective environment of the situation is more, combined with the child's physical condition, the resistance to infection factors is relatively low, so easy to repeated infection. And infection, often can not be given sufficient attention, timely or radical cure, leading to kidney cells damaged, and gradually deteriorated, and finally the development of uremia.

What are the symptoms of uremia in children?

1, loss of appetite or indigestion phenomenon, if the condition is serious, there will be anorexia, nausea, vomiting, diarrhea.

2, skin itching, which is common symptoms of uremic patients in the skin exposed parts, a slight contusion can cause skin ecchymosis.

3, breathing out of the gas smell of urine.

If the child appears above the abnormal situation, to do a timely check, has confirmed whether the child is healthy.

What causes the incidence of uremia in children?

According to the survey, the incidence of primary kidney disease caused by uremia in children from high to low were: chronic glomerulonephritis, chronic interstitial nephritis, congenital polycystic kidney disease, lupus nephritis and so on.

Here to introduce the two causes of uremia in children:

First, chronic nephritis

Chronic nephritis in children is an important cause of uremia. It follows glomerular disease → the pathogenesis of uremia, namely: glomerular disease is generally due to glomerular ischemia, hypoxia state, damage the glomerular capillary endothelial cells, to attract blood Inflammatory cells infiltration of inflammatory mediators, leading to clinical proteinuria, hematuria, and then the glomerular will gradually progress to fibrosis, sclerosis stage, when the inherent cell phenotype transformation, resulting in difficult to be degraded ECM, when the ECM Replace the healthy nephrons, functional nephrons gradually reduced, persistent renal function loss, a large number of kidney scar tissue generation, the kidneys lost the function of filtration and excretion, that is, to the stage of development of terminal renal failure.

Second, urinary tract infection

Pediatric urinary tract infection is one of the most common cause of interstitial nephritis, urinary tract infection by disease can be divided into acute urinary tract infection and chronic urinary tract infection. Acute urinary tract infection generally good prognosis, will not leave sequelae, it will not affect the renal function. But if the condition is delayed, it will cause chronic, repeated infection, reverse pathological damage, affecting the renal pelvis and then to the renal interstitial, resulting in kidney damage, leading to gradual fibrosis of the kidneys, the formation of kidney scars, and ultimately develop into poison.

Therefore, parents should be alert to the occurrence of these two diseases, to protect children's health.

Symptoms and causes of uremia in children

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