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What are the classification of polycystic kidney disease in

2017-11-20 16:47

Kidney disease is a great harm to the human body in recent years, polycystic kidney disease is one of them, because people lack of understanding of polycystic kidney disease, timely infection did not timely detection, which can not be timely treatment , Resulting in the exacerbations of the disease, serious words will endanger life, in fact, polycystic kidney disease has a variety of categories, then, polycystic kidney disease in what classification? The following experts to explain to you.

According to different genetic methods, can be pided into autosomal dominant polycystic kidney disease and often dyed recessive polycystic kidney disease. Autosomal recessive polycystic kidney disease, onset in infancy, clinical rare; autosomal dominant polycystic kidney disease, often found in the middle age of youth, but also in any age.

Polycystic kidney (ADPKD) is one of the most common single gene hereditary nephropathy, the incidence rate of 1/1000 ~ 1/4000, the age of onset in more than 30 to 50 years old, it is also known as "adult polycystic kidney disease" , In fact the disease can occur at any age, or even the fetus, so the "adult type" of the term is not accurate, is now used. ADPKD in addition to involving the kidney, but also associated with liver cysts, pancreatic cysts, intracranial aneurysms, heart valve abnormalities, therefore, it is also a systemic disease. At present, it has been clearly caused by polycystic kidney disease mutant genes are PKD1HE, PKD2 two. 50% of patients over 60 years of age will develop to end-stage renal failure, accounting for end-stage renal failure causes 5 to 10%.

Polycystic kidney disease (ARPKD) is a recessive hereditary nephropathy, usually in infancy that is obvious, so in the past known as "infant polycystic kidney disease", a small part occurred in children or adolescents. The incidence of about 1/10000 to 1/4 million, often accompanied by liver involvement, manifested as liver cysts. It has been found that its incidence and PKHD1 gene. ARPKD children, 50% in a few hours after birth to a few days died of respiratory failure or renal failure, survived to adults are the main features of the kidney collection tube spindle-shaped expansion, progress to renal failure, accompanied by intrahepatic bile duct dilatation, Congenital liver fibrosis, clinical manifestations of portal hypertension. As ARPKD is a rare disease, occurred in children.

The above content is on the "polycystic kidney disease in the classification of what?" This issue is to say, I believe we have a simple understanding of this disease for the polycystic kidney disease, we should learn more about this Of knowledge, to be aware of, even if the infection can also be the first time to respond, so that will not delay the disease.

 

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